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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis duri...

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis duri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e6956b0bc82403cacae878852daffc3

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

Publication information

Publisher

London: Nature Publishing Group UK

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Scope and Contents

Contents

Acute kidney injury (AKI) is morphologically characterized by a synchronized plasma membrane rupture of cells in a specific section of a nephron, referred to as acute tubular necrosis (ATN). Whereas the involvement of necroptosis is well characterized, genetic evidence supporting the contribution of ferroptosis is lacking. Here, we demonstrate that...

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Full title

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

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Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1e6956b0bc82403cacae878852daffc3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e6956b0bc82403cacae878852daffc3

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-24712-6

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