Lipolysis regulates major transcriptional programs in brown adipocytes
Lipolysis regulates major transcriptional programs in brown adipocytes
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative metabolism. We have used pharmacological inhibitors and a direct activator of lipolysis to acutely modulate the activity of lipases, thereby enabling us to uncover lip...
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Lipolysis regulates major transcriptional programs in brown adipocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_1e86f6f9fe4740609f82a4f4f6dca1cc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e86f6f9fe4740609f82a4f4f6dca1cc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31525-8