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Lipolysis regulates major transcriptional programs in brown adipocytes

Lipolysis regulates major transcriptional programs in brown adipocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e86f6f9fe4740609f82a4f4f6dca1cc

Lipolysis regulates major transcriptional programs in brown adipocytes

About this item

Full title

Lipolysis regulates major transcriptional programs in brown adipocytes

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-07, Vol.13 (1), p.3956-3956, Article 3956

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative metabolism. We have used pharmacological inhibitors and a direct activator of lipolysis to acutely modulate the activity of lipases, thereby enabling us to uncover lip...

Alternative Titles

Full title

Lipolysis regulates major transcriptional programs in brown adipocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1e86f6f9fe4740609f82a4f4f6dca1cc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e86f6f9fe4740609f82a4f4f6dca1cc

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-31525-8

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