EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cance...
EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation
About this item
Full title
Author / Creator
Chen, Yang , Wang, Youyou , Zhao, Lujun , Wang, Ping , Sun, Jifeng , Bao, Rudi , Li, Chenghai and Liu, Ningbo
Publisher
China: Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy, Tianjin Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China%Jiangsu Hansoh Pharmaceutical Co., Ltd, Lianyungang 222069, China
Journal title
Language
English
Formats
Publication information
Publisher
China: Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy, Tianjin Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China%Jiangsu Hansoh Pharmaceutical Co., Ltd, Lianyungang 222069, China
Subjects
More information
Scope and Contents
Contents
To investigate the potential of HS-10182, a second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), as a radiosensitizer in non-small cell lung cancer (NSCLC).
Two cell lines of NSCLCs, A549 that possesses wild-type (WT) EGFRs and H1975 that possesses EGFR L858R/T790M double mutations, were treated with HS-10182...
Alternative Titles
Full title
EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1e902d59287e449da59c2c1188a32fb0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e902d59287e449da59c2c1188a32fb0
Other Identifiers
ISSN
2095-3941
E-ISSN
2095-3941
DOI
10.20892/j.issn.2095-3941.2017.0118
