Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibilit...
Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Novel coronavirus disease 2019 (COVID-19) has emerged as a global pandemic with far-reaching societal impact. Here we demonstrate that Pin1 is a key cellular molecule necessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) propagation. In this study, siRNA-mediated silencing of Pin1 expression markedly suppressed the proliferatio...
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Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target
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TN_cdi_doaj_primary_oai_doaj_org_article_1ea816cff4094d0dadc3628615db9c97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1ea816cff4094d0dadc3628615db9c97
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-97972-3
