In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1
In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1
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Author / Creator
Liu, Na , Chen, Ping , Du, Xiaojun , Sun, Junxia and Han, Shasha
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Obtusofolin is the major active ingredient of Catsia tora L., which possesses the activity of improving eyesight and protecting the optic nerve. Investigation on the interaction of obtusofolin with cytochrome P450 enzymes (CYP450s) could provide a reference for the clinical application of obtusofolin.
The effect of obtusofolin on the activity of...
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Full title
In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1
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TN_cdi_doaj_primary_oai_doaj_org_article_1eaa610e03cf40719bb4c96cfdbb3783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1eaa610e03cf40719bb4c96cfdbb3783
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ISSN
2662-7671
E-ISSN
2662-7671,1472-6882
DOI
10.1186/s12906-021-03397-w