Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacte...
Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The persistent increase of multidrug-resistant (MDR)
Mycobacterium tuberculosis
(
Mtb
) infections negatively impacts Tuberculosis treatment outcomes. Host-directed therapies (HDT) pose an complementing strategy, particularly since
Mtb
is highly successful in evading host-defense by manipulating host-signaling pathways. Here, we s...
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Full title
Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections
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TN_cdi_doaj_primary_oai_doaj_org_article_1ec152b467db4abebb49dc8f7a4e9c3c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1ec152b467db4abebb49dc8f7a4e9c3c
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-98980-z
