Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotrans...
Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Autoantibodies to the smaller isoform of glutamate decarboxylase (GAD) can be found in patients with type 1 diabetes and a number of neurological disorders, including stiff-person syndrome, cerebellar ataxia and limbic encephalitis. The detection of disease-specific autoantibody epitopes led to the hypothesis that distinct GAD autoantibodies may el...
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Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions
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TN_cdi_doaj_primary_oai_doaj_org_article_1edc1446dc3a4fa1b38b52c97c3a7f14
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1edc1446dc3a4fa1b38b52c97c3a7f14
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ISSN
1662-5153
E-ISSN
1662-5153
DOI
10.3389/fnbeh.2015.00078
