HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocyt...
HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Obesity is associated with the accumulation of dysfunctional adipose tissue that secretes several pro-inflammatory cytokines (adipocytokines). Recent studies have presented evidence that adipose tissues in obese individuals and animal models are hypoxic, which may result in upregulation and stabilization of the hypoxia inducible factor HIF1α. Epige...
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Full title
HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_1f1762355a5d402da6a49bfb3d0e5897
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f1762355a5d402da6a49bfb3d0e5897
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9010134
