Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immu...
Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immunotherapy
About this item
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Author / Creator
Guan, Meng , Cheng, Kai , Xie, Xiao-Ting , Li, Yong , Ma, Meng-Wen , Zhang, Bin , Chen, Si , Chen, Wei , Liu, Bo , Fan, Jin-Xuan and Zhao, Yuan-Di
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cuproptosis is an emerging mode of programmed cell death for tumor suppression but sometimes gets resisted by tumor cells resist under specific mechanisms. Inhibiting copper transporter ATPase (ATP7A) was found to disrupt copper ion homeostasis, thereby enhancing the effect of cuproptosis and eventually inhibiting tumor invasion and metastasis. In...
Alternative Titles
Full title
Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immunotherapy
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1f201d2373334c37a30cd8c111d38a58
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f201d2373334c37a30cd8c111d38a58
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54469-7
