Hearing impairment due to Mir183/96/182 mutations suggests both loss-of-function and gain-of-functio...
Hearing impairment due to Mir183/96/182 mutations suggests both loss-of-function and gain-of-function effects
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Publisher
Cambridge: The Company of Biologists Ltd
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Language
English
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Publisher
Cambridge: The Company of Biologists Ltd
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Contents
The microRNA miR-96 is important for hearing, as point mutations in humans and mice result in dominant progressive hearing loss. Mir96 is expressed in sensory cells along with Mir182 and Mir183, but the roles of these closely-linked microRNAs are as yet unknown. Here, we analyse mice carrying null alleles of Mir182, and of Mir183 and Mir96 together...
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Full title
Hearing impairment due to Mir183/96/182 mutations suggests both loss-of-function and gain-of-function effects
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TN_cdi_doaj_primary_oai_doaj_org_article_1f431935b8b34900a4667b980d91afe7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f431935b8b34900a4667b980d91afe7
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.047225
