Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atheros...
Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Despite widespread use of statins to reduce low-density lipoprotein cholesterol (LDL-C) and associated atherosclerotic cardiovascular risk, many patients do not achieve sufficient LDL-C lowering due to muscle-related side effects, indicating novel treatment strategies are required. Bempedoic acid (ETC-1002) is a small molecule intended to lower LDL...
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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
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TN_cdi_doaj_primary_oai_doaj_org_article_1f66c328c6054aecb4400856a6c02de9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f66c328c6054aecb4400856a6c02de9
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2041-1723
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2041-1723
DOI
10.1038/ncomms13457