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The translation elongation factor eEF1A1 couples transcription to translation during heat shock resp...

The translation elongation factor eEF1A1 couples transcription to translation during heat shock resp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f9f7be653c44fb5ab7db6c16b72293f

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

About this item

Full title

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2014-09, Vol.3, p.e03164

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Translation elongation factor eEF1A has a well-defined role in protein synthesis. In this study, we demonstrate a new role for eEF1A: it participates in the entire process of the heat shock response (HSR) in mammalian cells from transcription through translation. Upon stress, isoform 1 of eEF1A rapidly activates transcription of HSP70 by recruiting...

Alternative Titles

Full title

The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1f9f7be653c44fb5ab7db6c16b72293f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1f9f7be653c44fb5ab7db6c16b72293f

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.03164

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