Inadequate BiP availability defines endoplasmic reticulum stress
Inadequate BiP availability defines endoplasmic reticulum stress
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy chain (μs) thanks to the unfolded protein response (UPR; Bakunts et al., 2017). Here we show that con...
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Inadequate BiP availability defines endoplasmic reticulum stress
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TN_cdi_doaj_primary_oai_doaj_org_article_1fadbf5d07454278a95cd18f5e2395cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fadbf5d07454278a95cd18f5e2395cb
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.41168