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Inadequate BiP availability defines endoplasmic reticulum stress

Inadequate BiP availability defines endoplasmic reticulum stress

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fadbf5d07454278a95cd18f5e2395cb

Inadequate BiP availability defines endoplasmic reticulum stress

About this item

Full title

Inadequate BiP availability defines endoplasmic reticulum stress

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-03, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy chain (μs) thanks to the unfolded protein response (UPR; Bakunts et al., 2017). Here we show that con...

Alternative Titles

Full title

Inadequate BiP availability defines endoplasmic reticulum stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1fadbf5d07454278a95cd18f5e2395cb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fadbf5d07454278a95cd18f5e2395cb

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.41168

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