Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation
Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation
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Bogor: Bogor Agricultural University (IPB), Department of Biology
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English
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Bogor: Bogor Agricultural University (IPB), Department of Biology
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Proflavine, an acridine dye, is a known DNA intercalating agent. In the present study, we show that proflavine alone on photoillumination can generate reactive oxygen species (ROS). These proflavine-derived ROS cause damage to proteins, and this effect is enhanced when the divalent metal ion Cu (II) is included in the reaction. Bathocuproine, a spe...
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Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation
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TN_cdi_doaj_primary_oai_doaj_org_article_1fafbaacea2246b08f7d9305cff95623
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fafbaacea2246b08f7d9305cff95623
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ISSN
1978-3019
E-ISSN
2086-4094
DOI
10.1016/j.hjb.2017.09.005
