Super multiple primary lung cancers harbor high-frequency BRAF and low-frequency EGFR mutations in t...
Super multiple primary lung cancers harbor high-frequency BRAF and low-frequency EGFR mutations in the MAPK pathway
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Li, Haochen , Huang, Zhicheng , Guo, Chao , Wang, Yadong , Li, Bowen , Wang, Sha , Bai, Na , Chen, Hanlin , Xue, Jianchao , Wang, Daoyun , Zheng, Zhibo , Bing, Zhongxing , Song, Yang , Xu, Yuan , Huang, Guanghua , Yu, Xiaoqing , Li, Ruirui , Fung, Ka Luk , Li, Ji , Song, Lan , Zhu, Ziwei , Liu, Songtao , Liang, Naixin and Li, Shanqing
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The incidence of multiple primary lung cancer (MPLC) is increasing, with some of our surgical patients exhibiting numerous lesions. We defined lung cancer with five or more primary lesions as super MPLCs. Elucidating the genomic characteristics of this special MPLC subtype can help reduce disease burden and understand tumor evolution. In our cohort...
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Super multiple primary lung cancers harbor high-frequency BRAF and low-frequency EGFR mutations in the MAPK pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_1fe49a62be4f4c158cd35c74e8f07d97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1fe49a62be4f4c158cd35c74e8f07d97
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ISSN
2397-768X
E-ISSN
2397-768X
DOI
10.1038/s41698-024-00726-3
