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Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung inju...

Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung inju...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_20291314aac84006a87fe826f8a5b72d

Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3

About this item

Full title

Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3

Publisher

England: BioMed Central Ltd

Journal title

Respiratory research, 2024-07, Vol.25 (1), p.291-15, Article 291

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Acute lung injury (ALI) is characterized by an unregulated inflammatory reaction, often leading to severe morbidity and ultimately death. Excessive inflammation caused by M1 macrophage polarization and pyroptosis has been revealed to have a critical role in ALI. Recent study suggests that glycolytic reprogramming is important in the regulation of m...

Alternative Titles

Full title

Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_20291314aac84006a87fe826f8a5b72d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_20291314aac84006a87fe826f8a5b72d

Other Identifiers

ISSN

1465-993X,1465-9921

E-ISSN

1465-993X

DOI

10.1186/s12931-024-02926-8

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