Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung inju...
Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3
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Author / Creator
Zhu, Guiyin , Yu, Haiyang , Peng, Tian , Yang, Kun , Xu, Xue and Gu, Wen
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Acute lung injury (ALI) is characterized by an unregulated inflammatory reaction, often leading to severe morbidity and ultimately death. Excessive inflammation caused by M1 macrophage polarization and pyroptosis has been revealed to have a critical role in ALI. Recent study suggests that glycolytic reprogramming is important in the regulation of m...
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Glycolytic enzyme PGK1 promotes M1 macrophage polarization and induces pyroptosis of acute lung injury via regulation of NLRP3
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TN_cdi_doaj_primary_oai_doaj_org_article_20291314aac84006a87fe826f8a5b72d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_20291314aac84006a87fe826f8a5b72d
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ISSN
1465-993X,1465-9921
E-ISSN
1465-993X
DOI
10.1186/s12931-024-02926-8