N6-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC...
N6-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming
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Zhou, Mingxia , He, Jing , Li, Yingxia , Jiang, Libin , Ran, Jiaxuan , Wang, Chang , Ju, Chenxi , Du, Dan , Xu, Xinyu , Wang, Xuexin , Li, Hongle , He, Fucheng and Wen, Hongtao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aerobic glycolysis has been considered as a hallmark of colorectal cancer (CRC). However, the potential functional regulators of glycolysis in CRC remains to be elucidated. In the current study, we found that Regenerating islet-derived protein 1-alpha (REG1α) was significantly increased in both CRC tissues and serum, and positively associated with...
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Full title
N6-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming
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TN_cdi_doaj_primary_oai_doaj_org_article_2031322543b04c89a7c00d832a1609ce
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2031322543b04c89a7c00d832a1609ce
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-06067-6
