Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease
Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia and behavioral changes. Extracellular deposition of amyloid plaques (Aβ) and intracellular deposition of neurofibrillary tangles in neurons are the major pathogenicities of AD. However, drugs targeting these therapeutic targets are not effective. Therefore,...
Alternative Titles
Full title
Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2059ccfe55644e8bae90c637012f62df
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2059ccfe55644e8bae90c637012f62df
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-99562-9
