RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11...
RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13
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Author / Creator
Zhang, Zhi‐Dong , Li, Hong‐Xu , Gan, Hu , Tang, Zhen , Guo, Yu‐Yao , Yao, Shu‐Qi , Liuyu, Tianzi , Zhong, Bo and Lin, Dandan
Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
The subcellular localization and intracellular trafficking of Toll‐like receptors (TLRs) critically regulate TLRs‐mediated antimicrobial immunity and autoimmunity. Here, it is demonstrated that the E3 ubiquitin ligase RNF115 inhibits the post‐endoplasmic reticulum (ER) trafficking of TLRs and TLRs‐mediated immune responses by catalyzing ubiquitinat...
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Full title
RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13
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TN_cdi_doaj_primary_oai_doaj_org_article_20f8075a907944e8b30036df68263be5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_20f8075a907944e8b30036df68263be5
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202105391