DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
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Cambridge: eLife Sciences Publications Ltd
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Language
English
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Publisher
Cambridge: eLife Sciences Publications Ltd
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Contents
DNA double-strand break (DSB) repair by homologous recombination is confined to the S and G
2
phases of the cell cycle partly due to 53BP1 antagonizing DNA end resection in G
1
phase and non-cycling quiescent (G
0
) cells where DSBs are predominately repaired by non-homologous end joining (NHEJ). Unexpectedly, we uncovered extensi...
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Full title
DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
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TN_cdi_doaj_primary_oai_doaj_org_article_20fdda038d0c46f1ba37279b0a8d1e09
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_20fdda038d0c46f1ba37279b0a8d1e09
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.74700
