Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertr...
Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis
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England: The Company of Biologists Ltd
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Language
English
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England: The Company of Biologists Ltd
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HIRA is the histone chaperone responsible for replication-independent incorporation of histone variant H3.3 within gene bodies and regulatory regions of actively transcribed genes, and within the bivalent promoter regions of developmentally regulated genes. The HIRA gene lies within the 22q11.2 deletion syndrome critical region; individuals with th...
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Full title
Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis
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TN_cdi_doaj_primary_oai_doaj_org_article_21433f80557d434da98d5493f24423dc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21433f80557d434da98d5493f24423dc
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.022889
