Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mic...
Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Bistable motoneurons of the spinal cord exhibit warmth-activated plateau potential driven by Na
+
and triggered by a brief excitation. The thermoregulating molecular mechanisms of bistability and their role in motor functions remain unknown. Here, we identify thermosensitive Na
+
-permeable Trpm5 channels as the main molecular players f...
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Full title
Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_214612d1787d4019a823b0b8efb12a75
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_214612d1787d4019a823b0b8efb12a75
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27113-x
