Application of 4D-QSAR studies to a series of raloxifene analogs and design of potential selective e...
Application of 4D-QSAR studies to a series of raloxifene analogs and design of potential selective estrogen receptor modulators
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
Four-dimensional quantitative structure-activity relationship (4D-QSAR) analysis was applied on a series of 54 2-arylbenzothiophene derivatives, synthesized by Grese and coworkers, based on raloxifene (an estrogen receptor-alpha antagonist), and evaluated as ERa ligands and as inhibitors of estrogen-stimulated proliferation of MCF-7 breast cancer c...
Alternative Titles
Full title
Application of 4D-QSAR studies to a series of raloxifene analogs and design of potential selective estrogen receptor modulators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_218a2447da1c441ca08e5de776272929
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_218a2447da1c441ca08e5de776272929
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules17067415
