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Accurate quantification of circular RNAs identifies extensive circular isoform switching events

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_219f0d0bf5fa43b09bef99e959b408e2

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

About this item

Full title

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-01, Vol.11 (1), p.90-14, Article 90

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and RNase R treatment efficiency, and underestimation of back-spliced junction reads. Here, we propose a novel algorithm, CIRIquant, for accurate circRNA quantification and differential expression...

Alternative Titles

Full title

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_219f0d0bf5fa43b09bef99e959b408e2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_219f0d0bf5fa43b09bef99e959b408e2

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13840-9

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