Accurate quantification of circular RNAs identifies extensive circular isoform switching events
Accurate quantification of circular RNAs identifies extensive circular isoform switching events
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and RNase R treatment efficiency, and underestimation of back-spliced junction reads. Here, we propose a novel algorithm, CIRIquant, for accurate circRNA quantification and differential expression...
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Accurate quantification of circular RNAs identifies extensive circular isoform switching events
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TN_cdi_doaj_primary_oai_doaj_org_article_219f0d0bf5fa43b09bef99e959b408e2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_219f0d0bf5fa43b09bef99e959b408e2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13840-9