Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotre...
Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
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New Zealand: Dove Medical Press Limited
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English
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Publisher
New Zealand: Dove Medical Press Limited
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The low penetration of drugs across the blood-brain barrier (BBB) compromises the delivery of chemotherapeutic agents to the brain parenchyma and contributes to the poor prognosis of glioblastoma multiforme (GBM). We investigated the efficacy of methotrexate-loaded lipid-core nanocapsules (MTX-LNC) administered by the oral route to treat murine GBM...
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Full title
Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
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TN_cdi_doaj_primary_oai_doaj_org_article_21ac1c69d18848859314153c60906e2a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21ac1c69d18848859314153c60906e2a
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ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S168400
