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HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmo...

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21ad722718874b2cb2712a1a9ed64d7b

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

About this item

Full title

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-01, Vol.11 (1), p.1468-1468, Article 1468

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic dysfunction. The mechanisms that transduce these mechanical forces are not fully understood. Our...

Alternative Titles

Full title

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_21ad722718874b2cb2712a1a9ed64d7b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21ad722718874b2cb2712a1a9ed64d7b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-80882-1

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