Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-...
Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 111In-tilmanocept
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Author / Creator
Varasteh, Zohreh , Hyafil, Fabien , Anizan, Nadège , Diallo, Devy , Aid-Launais, Rachida , Mohanta, Sarajo , Li, Yuanfang , Braeuer, Miriam , Steiger, Katja , Vigne, Jonathan , Qin, Zhengtao , Nekolla, Stephan G. , Fabre, Jean-Etienne , Döring, Yvonne , Le Guludec, Dominique , Habenicht, Andreas , Vera, David R. and Schwaiger, Markus
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
Atherosclerotic plaque phenotypes are classified based on the extent of macrophage infiltration into the lesions, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR) is over-expressed in activated macrophages. Tilmanocept is a tracer that targets MR and is approved in Euro...
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Full title
Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 111In-tilmanocept
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TN_cdi_doaj_primary_oai_doaj_org_article_21cd2adc52904003bef1f3cbf60ab51d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21cd2adc52904003bef1f3cbf60ab51d
Other Identifiers
ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-017-0287-y