RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive r...
RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Autosomal Recessive Renal Tubular Dysgenesis (AR-RTD) is a fatal genetic disorder characterized by complete absence or severe depletion of proximal tubules (PT) in patients harboring pathogenic variants in genes involved in the Renin–Angiotensin–Aldosterone System. To uncover the pathomechanism of AR-RTD, differentiation of
ACE-/-
and
AGTR...
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RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_21f90e81a5fe4cb28b323e95f795a5d6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21f90e81a5fe4cb28b323e95f795a5d6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43795-x