Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disor...
Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes
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Cairo, Egypt: Hindawi Publishing Corporation
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English
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Cairo, Egypt: Hindawi Publishing Corporation
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Our hypothesis is that allosteric receptor-receptor interactions in homo- and heteroreceptor complexes may form the molecular basis of learning and memory. This principle is illustrated by showing how cocaine abuse can alter the adenosine A2AR-dopamine D2R heterocomplexes and their receptor-receptor interactions and hereby induce neural plasticity...
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Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes
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TN_cdi_doaj_primary_oai_doaj_org_article_21faf16683ef49559aa3f5ce9d99b257
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_21faf16683ef49559aa3f5ce9d99b257
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ISSN
2090-5904
E-ISSN
1687-5443
DOI
10.1155/2016/4827268
