Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEA...
Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the most potent IFN inducer. In in vivo mouse studies, intraperitoneal injection of Poly (I:C) elicited IFN-α/β production and natural killer (NK...
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Full title
Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells
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TN_cdi_doaj_primary_oai_doaj_org_article_22260b8bb2a449f7a4f8a1bb2afa08c4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22260b8bb2a449f7a4f8a1bb2afa08c4
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ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/1743-422X-9-114
