ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid diso...
ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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ANTXR1 is one of two cell surface receptors mediating the uptake of the anthrax toxin into cells. Despite substantial research on its role in anthrax poisoning and a proposed function as a collagen receptor, ANTXR1’s physiological functions remain largely undefined. Pathogenic variants in ANTXR1 lead to the rare GAPO syndrome, named for its four pr...
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ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder
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TN_cdi_doaj_primary_oai_doaj_org_article_22356ec8dc874494a392ca8895a39007
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22356ec8dc874494a392ca8895a39007
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ISSN
2045-2322
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2045-2322
DOI
10.1038/s41598-024-59901-y