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ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid diso...

ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid diso...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22356ec8dc874494a392ca8895a39007

ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder

About this item

Full title

ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-04, Vol.14 (1), p.9321-9321, Article 9321

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ANTXR1 is one of two cell surface receptors mediating the uptake of the anthrax toxin into cells. Despite substantial research on its role in anthrax poisoning and a proposed function as a collagen receptor, ANTXR1’s physiological functions remain largely undefined. Pathogenic variants in ANTXR1 lead to the rare GAPO syndrome, named for its four pr...

Alternative Titles

Full title

ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_22356ec8dc874494a392ca8895a39007

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22356ec8dc874494a392ca8895a39007

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-59901-y

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