RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative brea...
RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells
About this item
Full title
Author / Creator
Peng, Jin , Tang, Lichun , Cai, Mengjiao , Chen, Huan , Wong, Jiemin and Zhang, Pumin
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Triple‐negative breast cancer (TNBC) is a malignancy that currently lacks targeted therapies. The majority of TNBCs can be characterized as basal‐like and has an expression profile enriched with genes involved in DNA damage repair and checkpoint response. Here, we report that TNBC cells are under replication stress and are constantly generating DNA...
Alternative Titles
Full title
RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_22764bbdcb364bc4b404c85a7df3b4b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22764bbdcb364bc4b404c85a7df3b4b9
Other Identifiers
ISSN
2045-7634
E-ISSN
2045-7634
DOI
10.1002/cam4.2349
