Crizotinib-induced immunogenic cell death in non-small cell lung cancer
Crizotinib-induced immunogenic cell death in non-small cell lung cancer
About this item
Full title
Author / Creator
Liu, Peng , Zhao, Liwei , Pol, Jonathan , Levesque, Sarah , Petrazzuolo, Adriana , Pfirschke, Christina , Engblom, Camilla , Rickelt, Steffen , Yamazaki, Takahiro , Iribarren, Kristina , Senovilla, Laura , Bezu, Lucillia , Vacchelli, Erika , Sica, Valentina , Melis, Andréa , Martin, Tiffany , Xia, Lin , Yang, Heng , Li, Qingqing , Chen, Jinfeng , Durand, Sylvère , Aprahamian, Fanny , Lefevre, Deborah , Broutin, Sophie , Paci, Angelo , Bongers, Amaury , Minard-Colin, Veronique , Tartour, Eric , Zitvogel, Laurence , Apetoh, Lionel , Ma, Yuting , Pittet, Mikael J. , Kepp, Oliver and Kroemer, Guido
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immunogenic cell death (ICD) converts dying cancer cells into a therapeutic vaccine and stimulates antitumor immune responses. Here we unravel the results of an unbiased screen identifying high-dose (10 µM) crizotinib as an ICD-inducing tyrosine kinase inhibitor that has exceptional antineoplastic activity when combined with non-ICD inducing chemot...
Alternative Titles
Full title
Crizotinib-induced immunogenic cell death in non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Zhao, Liwei
Pol, Jonathan
Levesque, Sarah
Petrazzuolo, Adriana
Pfirschke, Christina
Engblom, Camilla
Rickelt, Steffen
Yamazaki, Takahiro
Iribarren, Kristina
Senovilla, Laura
Bezu, Lucillia
Vacchelli, Erika
Sica, Valentina
Melis, Andréa
Martin, Tiffany
Xia, Lin
Yang, Heng
Li, Qingqing
Chen, Jinfeng
Durand, Sylvère
Aprahamian, Fanny
Lefevre, Deborah
Broutin, Sophie
Paci, Angelo
Bongers, Amaury
Minard-Colin, Veronique
Tartour, Eric
Zitvogel, Laurence
Apetoh, Lionel
Ma, Yuting
Pittet, Mikael J.
Kepp, Oliver
Kroemer, Guido
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_228ee56caf814e7fbcca341ed093aaed
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_228ee56caf814e7fbcca341ed093aaed
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09415-3
