From Venom to Vein: Factor VII Activation as a Major Pathophysiological Target for Procoagulant Aust...
From Venom to Vein: Factor VII Activation as a Major Pathophysiological Target for Procoagulant Australian Elapid Snake Venoms
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Australian elapid snake venoms are uniquely procoagulant, utilizing blood clotting enzyme Factor Xa (FXa) as a toxin, which evolved as a basal trait in this clade. The subsequent recruitment of Factor Va (FVa) as a toxin occurred in the last common ancestor of taipans (Oxyuranus species) and brown snakes (Pseudonaja species). Factor II (prothrombin...
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Full title
From Venom to Vein: Factor VII Activation as a Major Pathophysiological Target for Procoagulant Australian Elapid Snake Venoms
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TN_cdi_doaj_primary_oai_doaj_org_article_229086f38e7d45ae8b430c975e621659
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_229086f38e7d45ae8b430c975e621659
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins16100430
