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IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial...

IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22c7bdafd0ce4da1b989232ea227fd06

IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

About this item

Full title

IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Publisher

England: BioMed Central

Journal title

BMC ophthalmology, 2024-03, Vol.24 (1), p.144-144, Article 144

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

To elaborate the underlying mechanisms by which IL-1β promote progression of Dry eye disease(DED) through effect on pyroptosis and apoptosis of corneal epithelial cells(CECs).
400 mOsM solutions were used to establish the DED model (hCECs- DED). RT-qPCR was performed to measure IL-1β mRNA and miR-146a-5p in CECs. Western blotting was performed t...

Alternative Titles

Full title

IL-1β induced down-regulation of miR-146a-5p promoted pyroptosis and apoptosis of corneal epithelial cell in dry eye disease through targeting STAT3

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_22c7bdafd0ce4da1b989232ea227fd06

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22c7bdafd0ce4da1b989232ea227fd06

Other Identifiers

ISSN

1471-2415

E-ISSN

1471-2415

DOI

10.1186/s12886-024-03396-8

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