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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22cbc62f402c469c8f51f06c9578da54

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

About this item

Full title

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2018-08, Vol.16 (1), p.242-8, Article 242

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Tumor necrosis factor (TNF)-alpha was originally identified in the 1970s as the serum mediator of innate immunity capable of inducing hemorrhagic necrosis in tumors. Today, a wide spectrum of biological activities have been attributed to this molecule, and clinical translation has mainly occurred not in using it to treat cancer, but rather to inhib...

Alternative Titles

Full title

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_22cbc62f402c469c8f51f06c9578da54

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22cbc62f402c469c8f51f06c9578da54

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-018-1611-7

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