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eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphoryla...

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphoryla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22d057117123401086a68b774154e78c

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

About this item

Full title

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-04, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Hypoxia and consequent production of vascular endothelial growth factor A (VEGFA) promote blood vessel leakiness and edema in ocular diseases. Anti-VEGFA therapeutics may aggravate hypoxia; therefore, therapy development is needed.
Oxygen-induced retinopathy was used as a model to test the role of nitric oxide (NO) in pathological neovasculariza...

Alternative Titles

Full title

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_22d057117123401086a68b774154e78c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22d057117123401086a68b774154e78c

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.64944

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