Pathway-based analysis using reduced gene subsets in genome-wide association studies
Pathway-based analysis using reduced gene subsets in genome-wide association studies
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to small marginal effects. Pathway level analysis incorporating prior biological information offers another way to analyze GWAS's of complex diseases, and promises to reveal the mechanism...
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Full title
Pathway-based analysis using reduced gene subsets in genome-wide association studies
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TN_cdi_doaj_primary_oai_doaj_org_article_22f982932c514116a45b5924f796bec7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_22f982932c514116a45b5924f796bec7
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/1471-2105-12-17
