Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Endometrioid ovarian carcinoma (EnOC) demonstrates substantial clinical and molecular heterogeneity. Here, we report whole exome sequencing of 112 EnOC cases following rigorous pathological assessment. We detect a high frequency of mutation in
CTNNB1
(43%),
PIK3CA
(43%),
ARID1A
(36%),
PTEN
(29%),
KRAS
(26%),
TP53<...
Alternative Titles
Full title
Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
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TN_cdi_doaj_primary_oai_doaj_org_article_232b42338ac04ca39f011da44d0890a8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_232b42338ac04ca39f011da44d0890a8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18819-5
