CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage com...
CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The sequential generation of layer-specific cortical neurons requires radial glia cells (RGCs) to precisely balance self-renewal and lineage commitment. While specific cell-cycle phases have been associated with these decisions, the mechanisms linking the cell-cycle machinery to cell-fate commitment remain obscure. Using single-cell RNA-sequencing,...
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CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment
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TN_cdi_doaj_primary_oai_doaj_org_article_233448a846a14b9a858b7a56acc46218
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_233448a846a14b9a858b7a56acc46218
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16597-8
