Redundancy in Innate Immune Pathways That Promote CD8 + T-Cell Responses in AAV1 Muscle Gene Transfe...
Redundancy in Innate Immune Pathways That Promote CD8 + T-Cell Responses in AAV1 Muscle Gene Transfer
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
While adeno-associated viral (AAV) vectors are successfully used in a variety of in vivo gene therapy applications, they continue to be hampered by the immune system. Here, we sought to identify innate and cytokine signaling pathways that promote CD8
T-cell responses against the transgene product upon AAV1 vector administration to murine skeleta...
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Full title
Redundancy in Innate Immune Pathways That Promote CD8 + T-Cell Responses in AAV1 Muscle Gene Transfer
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TN_cdi_doaj_primary_oai_doaj_org_article_235dc1cd7e4c4ff192ef2bca2af8736c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_235dc1cd7e4c4ff192ef2bca2af8736c
Other Identifiers
ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v16101507
