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Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects i...

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_235e535189b245a89cf3e864c254e8bb

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

About this item

Full title

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

Publisher

England: BioMed Central Ltd

Journal title

Respiratory research, 2017-04, Vol.18 (1), p.64-14, Article 64

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Interleukin 6 (IL-6) is a predictive factor of poor prognosis in patients with acute respiratory distress syndrome (ARDS). However, its acute pulmonary hemodynamic effects and role in lung injury have not been investigated in a clinically relevant murine model of ARDS.
We used adult C57Bl6 wild-type (WT) and IL-6 knock-out (IL-6KO) mice. The ani...

Alternative Titles

Full title

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_235e535189b245a89cf3e864c254e8bb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_235e535189b245a89cf3e864c254e8bb

Other Identifiers

ISSN

1465-993X,1465-9921

E-ISSN

1465-993X,1465-9921

DOI

10.1186/s12931-017-0553-6

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