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Ligand-induced shifts in conformational ensembles that describe transcriptional activation

Ligand-induced shifts in conformational ensembles that describe transcriptional activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_236457d256c9411bb678f601ffd29649

Ligand-induced shifts in conformational ensembles that describe transcriptional activation

About this item

Full title

Ligand-induced shifts in conformational ensembles that describe transcriptional activation

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2022-10, Vol.11

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Nuclear receptors function as ligand-regulated transcription factors whose ability to regulate diverse physiological processes is closely linked with conformational changes induced upon ligand binding. Understanding how conformational populations of nuclear receptors are shifted by various ligands could illuminate strategies for the design of synth...

Alternative Titles

Full title

Ligand-induced shifts in conformational ensembles that describe transcriptional activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_236457d256c9411bb678f601ffd29649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_236457d256c9411bb678f601ffd29649

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.80140

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