Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed b...
Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide
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Author / Creator
The Netherlands Brain Bank , Netherlands Brain Bank , Strategiska forskningsområden (SFO) , Department of Experimental Medical Science , Kognitiv sjukdomsforskning , Cognitive disorders , LU profilområde: Proaktivt åldrande , Strategic research areas (SRA) , Clinical Memory Research , Department of Clinical Sciences, Lund , Lund University Profile areas , Lund University , LU Profile Area: Proactive Ageing , Sektion V , Profile areas and other strong research environments , Section V , Department of Clinical Sciences, Malmö , Faculty of Medicine , Medicinska fakulteten , Mass Spectrometry , Cellulär biomekanik , Institutionen för kliniska vetenskaper, Malmö , Institutionen för kliniska vetenskaper, Lund , Lunds universitet , Masspektrometri , Lunds universitets profilområden , Klinisk minnesforskning , Profilområden och andra starka forskningsmiljöer , MultiPark: Multidisciplinary research focused on Parkinson´s disease , Institutionen för experimentell medicinsk vetenskap , Cellular Biomechanics , Nuñez-Diaz, Cristina , Pocevičiūtė, Dovilė , Schultz, Nina , Welinder, Charlotte , Swärd, Karl and Wennström, Malin
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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More information
Scope and Contents
Contents
The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2 diabetes mellitus (T2DM), are toxic not only for the pancreas, but also for the brain. In the latter, IAPP is often found in vessels, where it is highly toxic for pericytes, mural cells that...
Alternative Titles
Full title
Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide
Authors, Artists and Contributors
Author / Creator
Netherlands Brain Bank
Strategiska forskningsområden (SFO)
Department of Experimental Medical Science
Kognitiv sjukdomsforskning
Cognitive disorders
LU profilområde: Proaktivt åldrande
Strategic research areas (SRA)
Clinical Memory Research
Department of Clinical Sciences, Lund
Lund University Profile areas
Lund University
LU Profile Area: Proactive Ageing
Sektion V
Profile areas and other strong research environments
Section V
Department of Clinical Sciences, Malmö
Faculty of Medicine
Medicinska fakulteten
Mass Spectrometry
Cellulär biomekanik
Institutionen för kliniska vetenskaper, Malmö
Institutionen för kliniska vetenskaper, Lund
Lunds universitet
Masspektrometri
Lunds universitets profilområden
Klinisk minnesforskning
Profilområden och andra starka forskningsmiljöer
MultiPark: Multidisciplinary research focused on Parkinson´s disease
Institutionen för experimentell medicinsk vetenskap
Cellular Biomechanics
Nuñez-Diaz, Cristina
Pocevičiūtė, Dovilė
Schultz, Nina
Welinder, Charlotte
Swärd, Karl
Wennström, Malin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_237474e1021e46ca980562fee8c36642
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_237474e1021e46ca980562fee8c36642
Other Identifiers
ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-023-01013-1
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