AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐M...
AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐Mediated Astrocyte Autophagy
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Author / Creator
Zhu, Dan‐Dan , Huang, Yue‐Lin , Guo, Song‐Yu , Li, Na , Yang, Xue‐Wei , Sui, Ao‐Ran , Wu, Qiong , Zhang, Yue , Kong, Yue , Li, Qi‐Fa , Zhang, Ting , Zheng, Wen‐Fei , Li, Ai‐Ping , Yu, Jian , Ma, Tong‐Hui and Li, Shao
Publisher
Weinheim: John Wiley & Sons, Inc
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English
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Weinheim: John Wiley & Sons, Inc
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The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects of AQP4 associated with SAE and reveal its underlying mechanism causing cognitive impairment. The in vivo experimental results reveal that AQP4 in peripheral blood of patients wi...
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Full title
AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐Mediated Astrocyte Autophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_2375907707e74f0ea06de1facf350953
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2375907707e74f0ea06de1facf350953
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202205862