Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone
About this item
Full title
Author / Creator
Im, Dohyun , Inoue, Asuka , Fujiwara, Takaaki , Nakane, Takanori , Yamanaka, Yasuaki , Uemura, Tomoko , Mori, Chihiro , Shiimura, Yuki , Kimura, Kanako Terakado , Asada, Hidetsugu , Nomura, Norimichi , Tanaka, Tomoyuki , Yamashita, Ayumi , Nango, Eriko , Tono, Kensuke , Kadji, Francois Marie Ngako , Aoki, Junken , Iwata, So and Shimamura, Tatsuro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In addition to the serotonin 5-HT
2A
receptor (5-HT
2A
R), the dopamine D
2
receptor (D
2
R) is a key therapeutic target of antipsychotics for the treatment of schizophrenia. The inactive state structures of D
2
R have been described in complex with the inverse agonists risperidone (D
2
R
ris
) and haloperi...
Alternative Titles
Full title
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone
Authors, Artists and Contributors
Author / Creator
Inoue, Asuka
Fujiwara, Takaaki
Nakane, Takanori
Yamanaka, Yasuaki
Uemura, Tomoko
Mori, Chihiro
Shiimura, Yuki
Kimura, Kanako Terakado
Asada, Hidetsugu
Nomura, Norimichi
Tanaka, Tomoyuki
Yamashita, Ayumi
Nango, Eriko
Tono, Kensuke
Kadji, Francois Marie Ngako
Aoki, Junken
Iwata, So
Shimamura, Tatsuro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_238cb5436dc34fefbac7633410b31405
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_238cb5436dc34fefbac7633410b31405
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20221-0
