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The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast...

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23a5f34fef334ff789f85c69f707a9be

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

About this item

Full title

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-02, Vol.11 (1), p.3176-3176, Article 3176

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking effective therapy. Many TNBCs show remarkable response to carboplatin-based chemotherapy, but often develop resistance over time. With increasing use of carboplatin in the clinic, there is a pressing need to identify vulnerabilities of carboplatin-resistant t...

Alternative Titles

Full title

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_23a5f34fef334ff789f85c69f707a9be

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23a5f34fef334ff789f85c69f707a9be

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-82780-6

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