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The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is In...

The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is In...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23a996ae5fec4f728a8d72c629d5772d

The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways

About this item

Full title

The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways

Publisher

New York: Hindawi

Journal title

Journal of immunology research, 2022-07, Vol.2022, p.1-13

Language

English

Formats

Publication information

Publisher

New York: Hindawi

More information

Scope and Contents

Contents

Type 1 interferons (IFN-1) are pleiotropic cytokines with well-established anticancer and antiviral properties, particularly in mucosal tissues. Hence, natural IFN-1-inducing treatments are highly sought after in the clinic. Here, we report for the first time that cryptolepine, a pharmacoactive alkaloid in the medicinal plant Cryptolepis sanguinole...

Alternative Titles

Full title

The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_23a996ae5fec4f728a8d72c629d5772d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23a996ae5fec4f728a8d72c629d5772d

Other Identifiers

ISSN

2314-8861

E-ISSN

2314-7156

DOI

10.1155/2022/8873536

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