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RO8191, a new compound for initiating embryo implantation in mice

RO8191, a new compound for initiating embryo implantation in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23b9e936cf8140889a79c5fd3040faba

RO8191, a new compound for initiating embryo implantation in mice

About this item

Full title

RO8191, a new compound for initiating embryo implantation in mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-09, Vol.15 (1), p.32387-11, Article 32387

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

During early pregnancy in mice, leukemia inhibitory factor (LIF) regulates embryo implantation by activating the JAK/STAT3 signaling pathway. The STAT3 pathway has been recognized to play a critical role in embryo implantation; however, it remains unclear whether STAT3 activation alone is sufficient to induce implantation. In this study, we investi...

Alternative Titles

Full title

RO8191, a new compound for initiating embryo implantation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_23b9e936cf8140889a79c5fd3040faba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23b9e936cf8140889a79c5fd3040faba

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-18471-3

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