Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumo...
Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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ABSTRACT
Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of telomeric silencing 1-like (DOT1L) is overexpressed in ov...
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Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_23c150ebe4db4cd3bdf5f05586a50b96
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_23c150ebe4db4cd3bdf5f05586a50b96
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2157-9024
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2157-9024
DOI
10.1038/s41389-021-00339-6
